Prospective Study of Lewis Antigen Alterations in the Gastric Precancerous Process1
نویسندگان
چکیده
A prospective study with two gastric biopsies taken several years apart was carried out in 1 1 7 subjects with intestinal metaplasia who are of the Lewis(a-b+) phenotype. They are residents of a rural Andean region in Colombia displaying very high rates of gastric cancer. The anamalous expression of Lewisa antigens in the metaplastic epithelium carried a significantly increased risk of colonic metaplasia and dysplasia. Such risk was much higher when the simultaneous expression of sulfomucins and Lewisa antigen was observed.
منابع مشابه
Prospective study of Lewis antigen alterations in the gastric precancerous process.
A prospective study with two gastric biopsies taken several years apart was carried out in 117 subjects with intestinal metaplasia who are of the Lewis(a-b+) phenotype. They are residents of a rural Andean region in Colombia displaying very high rates of gastric cancer. The anomalous expression of Lewis(a) antigens in the metaplastic epithelium carried a significantly increased risk of colonic ...
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